Article
Genomic and proteomic analyses of Mycobacterium bovis BCG Mexico 1931 reveal a diverse immunogenic repertoire against tuberculosis infection.
BMC genomics - 8 Oct 2011
Orduña Patricia, Cevallos Miguel A, de León Samuel Ponce, Arvizu Adriana, Hernández-González Ismael L, Mendoza-Hernández Guillermo, López-Vidal Yolanda
Abstract excerpt
BACKGROUND: Studies of Mycobacterium bovis BCG strains used in different countries and vaccination programs show clear variations in the genomes and immune protective properties of BCG strains. The aim of this study was to characterise the genomic and immune proteomic profile of the BCG 1931 strain used in Mexico. RESULTS: BCG Mexico 1931 has a circular chromosome of 4,350,386 bp with a G+C content and numbers of...
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