Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacteriophage-resistant mutants in Yersinia pestis: identification of phage receptors and attenuation for mice.

PloS one - 1 Jan 2011

Filippov Andrey A, Sergueev Kirill V, He Yunxiu, Huang Xiao-Zhe, Gnade Bryan T, Mueller Allen J, Fernandez-Prada Carmen M, Nikolich Mikeljon P

Abstract excerpt

BACKGROUND: Bacteriophages specific for Yersinia pestis are routinely used for plague diagnostics and could be an alternative to antibiotics in case of drug-resistant plague. A major concern of bacteriophage therapy is the emergence of phage-resistant mutants. The use of phage cocktails can overcome this problem but only if the phages exploit different receptors. Some phage-resistant mutants lose virulence and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages
Share to Lipopolysaccharides

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutagenesis, Site-Directed

Share to Plague

Share to Protein Transport

Share to Receptors, Virus

Share to Species Specificity

Share to Yersinia pestis

Source

Open in PubMed Open full text

Identifiers

PMID: 21980477
DOI: 10.1371/journal.pone.0025486
PMCID: PMC3182234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacteriophage-resistant mutants in Yersinia pestis: identification of phage receptors and attenuation for mice.PMID 21980477Read ↗

Bacteriophages of Yersinia pestis.Semantic proximity Read ↗

Interplays of mutations in waaA, cmk, and ail contribute to phage resistance in Yersinia pestis.Semantic proximity Read ↗

A perfect fit: Bacteriophage receptor-binding proteins for diagnostic and therapeutic applicationsSemantic proximity Read ↗

Chromosomally-Encoded Yersinia pestis Type III Secretion Effector Proteins Promote Infection in Cells and in MiceSemantic proximity Read ↗

Identification and impact on Pseudomonas aeruginosa virulence of mutations conferring resistance to a phage cocktail for phage therapy.Semantic proximity Read ↗

Phage therapy potentiates second-line antibiotic treatment against pneumonic plagueSemantic proximity Read ↗

Multireceptor phage cocktail against Salmonella enterica to circumvent phage resistanceSemantic proximity Read ↗

Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA.Semantic proximity Read ↗

Dissecting the invasion of <i>Galleria mellonella</i> by <i>Yersinia enterocolitica</i> reveals metabolic adaptations and a role of a phage lysis cassette in insect killingSemantic proximity Read ↗

Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation.Semantic proximity Read ↗

[Nature of bacterial phage receptors].Semantic proximity Read ↗

Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.