Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila.

Cell - 3 Jun 2005

King-Jones Kirst, Charles Jean-Philippe, Lam Geanette, Thummel Carl S

Abstract excerpt

A critical determinant of insect body size is the time at which the larva stops feeding and initiates wandering in preparation for metamorphosis. No genes have been identified that regulate growth by contributing to this key developmental decision to terminate feeding. We show here that mutations in the DHR4 orphan nuclear receptor result in larvae that precociously leave the food to form premature prepupae,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Ecdysone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Metamorphosis, Biological

Share to Neurosecretory Systems

Share to Receptors, Cytoplasmic and Nuclear

Source

Identifiers

PMID: 15935763
DOI: 10.1016/j.cell.2005.03.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila.PMID 15935763Read ↗

DHR3 is required for the prepupal-pupal transition and differentiation of adult structures during Drosophila metamorphosis.Semantic proximity Read ↗

The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis.Semantic proximity Read ↗

The Drosophila beta FTZ-F1 orphan nuclear receptor provides competence for stage-specific responses to the steroid hormone ecdysone.Semantic proximity Read ↗

Orphan nuclear receptor betaFTZ-F1 is required for muscle-driven morphogenetic events at the prepupal-pupal transition in Drosophila melanogaster.Semantic proximity Read ↗

Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila.Semantic proximity Read ↗

Ecdysone signaling in adult Drosophila melanogaster.Semantic proximity Read ↗

Posttranscriptional control of the competence factor betaFTZ-F1 by juvenile hormone in the mosquito Aedes aegypti.Semantic proximity Read ↗

Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development.Semantic proximity Read ↗

Essential roles for ecdysone signaling during Drosophila mid-embryonic development.Semantic proximity Read ↗

Functional Genomic Analysis of C. elegans MoltingSemantic proximity Read ↗

Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo.Semantic proximity Read ↗

The Drosophila ecdysone receptor (EcR) gene is required maternally for normal oogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.