Article
Identifying a new locus that regulates the development of rete ovarian cysts in MRL/MpJ mice.
The Japanese journal of veterinary research - 1 Aug 2011
Lee Shin-Hyo, Ichii Osamu, Otsuka Saori, Hashimoto Yoshiharu, Namiki Yuka, Kon Yasuhiro
Abstract excerpt
MRL/MpJ (MRL) is a mouse model for autoimmune disease and develops ovarian cysts with age. The ovarian cysts originate from the rete ovarii, which is considered to be the remnant of fetal mesonephric tubules. In a previous study, we analyzed the genetic background of ovarian cysts by using backcross progenies between MRL and C57BL/6N (B6) mice. By interval mapping, suggestive linkages were detected on several...
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