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Article

The MC4R(I251L) allele is associated with better metabolic status and more weight loss after gastric bypass surgery.

The Journal of clinical endocrinology and metabolism - 1 Dec 2011

Mirshahi Uyenlinh L, Still Christopher D, Masker Kathryn K, Gerhard Glenn S, Carey David J, Mirshahi Tooraj

Abstract excerpt

CONTEXT: Factors that influence long-term weight loss after Roux-en Y gastric bypass (RYGB) surgeries are poorly defined. The melanocortin system plays an important role in regulating energy homeostasis, satiety, and glucose metabolism. Variations of the MC4R comprise the most prevalent monogenetic obesity disorder. OBJECTIVE: The objective of the study was to examine the role of MC4R variants and diabetic status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21976721
DOI: 10.1210/jc.2011-1549
PMCID: PMC3232628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The MC4R(I251L) allele is associated with better metabolic status and more weight loss after gastric bypass surgery.PMID 21976721Read ↗

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