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Article

Weight and Glycemic Control Outcomes of Bariatric Surgery and Pharmacotherapy in Patients With Melanocortin-4 Receptor Deficiency.

Frontiers in endocrinology - 1 Jan 2021

Fojas Esphie Grace Fodra, Radha Saradalekshmi Koramannil, Ali Tomader, Nadler Evan P, Lessan Nader

Abstract excerpt

Background: Melanocortin-4 receptor (MC4R) mutations are the most common of the rare monogenic forms of obesity. However, the efficacy of bariatric surgery (BS) and pharmacotherapy on weight and glycemic control in individuals with MC4R deficiency (MC4R-d) is not well-established. We investigated and compared the outcomes of BS and pharmacotherapy in patients with and without MC4R-d. Methods: Pertinent details...

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Identifiers

PMID: 35095762
DOI: 10.3389/fendo.2021.792354
PMCID: PMC8793826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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