Article
Primary HIV-1 drug resistance in the C-terminal domains of viral reverse transcriptase among drug-naïve patients from Southern Brazil.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2011
Santos André F, Silveira Jussara, Muniz Cláudia P, Tornatore Michele, Góes Lívia R, Mendoza-Sassi Raul A, Martinez Ana M B, Tupinambás Unaí, Greco Dirceu B, Soares Marcelo A
Abstract excerpt
BACKGROUND: Major and accessory drug resistance mutations have been recently characterized in the C-terminal RT subdomains of HIV-1, connection and RNase H. However, their presence in treatment-naïve patients infected with HIV-1 non-B subtypes remains largely unknown. OBJECTIVES: To characterize the patterns of primary resistance at the C-terminal RT subdomains of HIV-1 infecting subjects in the southern region...
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