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Article

Estimation of modified concordance ratio in sib-pairs: effect of consanguinity on the risk of congenital heart diseases.

The international journal of biostatistics - 1 Jan 2010

Shoukri Mohamed M, Donner Allan, Dessouky Nadia Abdalla, Subhani Shazia, Al-Joufan Mansour, Al-Omrani Ahmed, Al-Mohanna Futwan, Al Halees Zohair Y

Abstract excerpt

Family studies are widely used for research into genetic and environmental influences on human traits. In this paper, we establish statistical methodology for the estimation of a new measure of sib similarity with respect to dichotomous traits measured on each member of within family sib-pair. We call this parameter "excess risk." For inference problems involving a single sample, we construct a large sample...

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PMID: 21969967
DOI: 10.2202/1557-4679.1216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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