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Article

Familial Aggregation and Heritability of Congenital Heart Defects.

Circulation journal : official journal of the Japanese Circulation Society - 25 Dec 2017

Kuo Chang-Fu, Lin Yu-Sheng, Chang Shang-Hung, Chou I-Jun, Luo Shue-Fen, See Lai-Chu, Yu Kuang-Hui, Huang Lu-Shuang, Chu Pao-Hsien

Abstract excerpt

BACKGROUND: Congenital heart defects (CHD) are known to cluster within families, but existing evidence varies for the estimates of familial relative risk (RR). We aimed to examine familial aggregation and heritability of CHD in the general population of Taiwan. METHODS AND RESULTS: We conducted a population-based family study using the Taiwan National Health Insurance (NHI) research database. Individuals with...

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PMID: 28824028
DOI: 10.1253/circj.CJ-17-0250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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