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Article

Detection of SEA-type α-thalassemia in embryo biopsies by digital PCR.

Taiwanese journal of obstetrics & gynecology - 1 Aug 2017

Lee Ta-Hsien, Hsu Ya-Chiung, Chang Chia Lin

Abstract excerpt

OBJECTIVE: Accurate and efficient pre-implantation genetic diagnosis (PGD) based on the analysis of single or oligo-cells is needed for timely identification of embryos that are affected by deleterious genetic traits in in vitro fertilization (IVF) clinics. Polymerase chain reaction (PCR) is the backbone of modern genetic diagnoses, and a spectrum of PCR-based techniques have been used to detect various...

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Source

Identifiers

PMID: 28805606
DOI: 10.1016/j.tjog.2017.03.002

Genes

SEA
PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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