Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro reconstitution of cdc25 regulated S. cerevisiae adenylyl cyclase and its kinetic properties.

The EMBO journal - 1 Mar 1990

Engelberg D, Simchen G, Levitzki A

Abstract excerpt

The attenuated GTP regulation adenylyl cyclase (CDC35) lysates or membranes prepared from cells of a cdc25ts strain is enhanced 2.5- to 6-fold by mixing these lysates or membranes with lysates or membranes from a cdc35ts strain harboring wild-type CDC25. The kinetics of activation of the Saccharomyces cerevisiae adenylyl cyclase in vitro is first order, as is the activation of mammalian adenylyl cyclase. The rate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Fungal Proteins
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Kinetics

Share to Plasmids

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 2155776
DOI: 10.1002/j.1460-2075.1990.tb08156.x
PMCID: PMC551717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro reconstitution of cdc25 regulated S. cerevisiae adenylyl cyclase and its kinetic properties.PMID 2155776Read ↗

Properties of the SDC25 C-domain, a GDP to GTP exchange factor of RAS proteins and in vitro modulation of adenylyl cyclase.Semantic proximity Read ↗

A Candida albicans homolog of CDC25 is functional in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Cdc25 protein of Saccharomyces cerevisiae is required for normal glucose transport.Semantic proximity Read ↗

Analysis of the role of the hypervariable region of yeast Ras2p and its farnesylation in the interaction with exchange factors and adenylyl cyclase.Semantic proximity Read ↗

Inactivation of the CDC25 gene product in Saccharomyces cerevisiae leads to a decrease in glycolytic activity which is independent of cAMP levels.Semantic proximity Read ↗

The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutagenic alteration of the distal switch II region of RAS blocks CDC25-dependent signaling functions.Semantic proximity Read ↗

The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras.Semantic proximity Read ↗

Interaction between the Saccharomyces cerevisiae CDC25 gene product and mammalian ras.Semantic proximity Read ↗

Ras-pathway has a dual role in yeast galactose metabolism.Semantic proximity Read ↗

Cdc25 is not the signal receiver for glucose induced cAMP response in S. cerevisiae.Semantic proximity Read ↗

Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.