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Three small partner proteins facilitate the type VII-dependent secretion of an antibacterial nuclease

10 Oct 2023

Abstract excerpt

ABSTRACT The type VIIb secretion system (T7SSb) is a multisubunit protein export machine found in Gram-positive Bacillota which plays a key role in interbacterial competition. The T7SSb secretes a variety of toxic effector proteins targeting closely related strains; however, the mechanism of secretion and the roles of numerous conserved genes within T7SSb gene clusters remain unknown. EsaD is a nuclease toxin...

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PMID: 37815362
DOI: 10.1128/mbio.02100-23

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