Article
Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase.
Journal of virology - 1 Aug 1990
Partin K, Kräusslich H G, Ehrlich L, Wimmer E, Carter C
Abstract excerpt
Proteolytic processing of the gag/pol precursor by the human immunodeficiency virus type 1 proteinase is essential for the production of infectious viral particles. Although the sites of virus-specific cleavages have been determined, the primary amino acid sequences surrounding these sites are heterogeneous and the determinants that direct the cleavage specificity exhibited by human immunodeficiency virus type 1...
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