Article
Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase.
Journal of virology - 1 Aug 1990
Partin K, Kräusslich H G, Ehrlich L, Wimmer E, Carter C
Abstract excerpt
Proteolytic processing of the gag/pol precursor by the human immunodeficiency virus type 1 proteinase is essential for the production of infectious viral particles. Although the sites of virus-specific cleavages have been determined, the primary amino acid sequences surrounding these sites are he...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Endopeptidases
- Escherichia coli
- Fusion Proteins, gag-pol
- Gene Products, gag
- Gene Products, pol
- HIV Protease
- HIV-1
- Molecular Sequence Data
- Mutation
- Plasmids
- Polymerase Chain Reaction
- Protein Biosynthesis
- Protein Processing, Post-Translational
- Rabbits
- Reticulocytes