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Article

Mutational analysis of a native substrate of the HIV-1 proteinase.

Advances in experimental medicine and biology - 1 Jan 1991

Partin K, Wimmer E, Carter C

Abstract excerpt

The purpose of this study was to define further the determinants of substrate specificity of HIV-1 PR. Rather than using small peptides, we used an in vitro system which permitted us to evaluate the effect of a mutated site within the context of its natural precursor. We made single-amino-acid substitutions around two sites which are processed by the HIV-1 PR. The Tyr/Pro site within gag appears to encode highly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Sequence Homology, Nucleic Acid

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Source

Identifiers

PMID: 1667451
DOI: 10.1007/978-1-4684-6012-4_65

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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