Article
Effect of genetically determined immunodeficiency on epidermal dendritic cell populations in C57BL/6J mice.
Archives of dermatological research - 1 Jan 1990
Sprecher E, Becker Y, Kraal G, Hall E, Shultz L D
Abstract excerpt
Mice homozygous for three different recessive mutations known to cause pleiotropic defects in the immune system and in the skin were used to evaluate the relationship between the classical immune system and dendritic epidermal cell populations. Numbers of Langerhans cells (LCs) and Thy-1+ dendritic cells (Thy-1+DEC) were determined using indirect immunofluorescence microscopy of epidermal whole mounts taken from...
Topics
- Animals
- Dendritic Cells
- Epidermal Cells
- Epidermis
- Fluorescent Antibody Technique
- Immune Tolerance
- Langerhans Cells
- Mice
- Mice, Mutant Strains
- Mutation