Dendritic-like cells from relB mutant mice.

doi:10.1007/978-1-4757-9966-8_8

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Article

Dendritic-like cells from relB mutant mice.

Advances in experimental medicine and biology - 1 Jan 1997

DiMolfetto L, Reilly C, Wei Q, Lo D

Abstract excerpt

Mice deficient in the NF-kappa B transcription factor relB appear to have defects in the production of mature dendritic cells, as secondary lymphoid tissues are absent, and spleen cells show a significant loss of antigen presenting function. Moreover, the thymus appears to be impaired in negative...

Topics

Animals
Antigen Presentation
Cell Differentiation
Dendritic Cells
Lymphocyte Activation
Mice
Mice, Mutant Strains
Mutation
Phenotype
Proto-Oncogene Proteins
T-Lymphocytes
Transcription Factor RelB
Transcription Factors

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