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Article

Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities.

Applied microbiology and biotechnology - 1 Feb 2012

Han Ah Reum, Shinde Pramod B, Park Je Won, Cho Jaeyong, Lee So Ra, Ban Yeon Hee, Yoo Young Ji, Kim Eun Ji, Kim Eunji, Park Sung Ryeol, Kim Byung-Gee, Lee Dong Gun, Yoon Yeo Joon

Abstract excerpt

A 14-membered macrolide antibiotic narbomycin produced from Streptomyces venezuelae ATCC 15439 is composed of polyketide macrolactone ring and D-desosamine as a deoxysugar moiety, which acts as an important determinant of its antibacterial activity. In order to generate diverse glycosylated derivatives of narbomycin, expression plasmids carrying different deoxysugar biosynthetic gene cassettes and the gene...

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PMID: 21959378
DOI: 10.1007/s00253-011-3592-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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