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Article

Over expression of IL-10 by macrophages overcomes resistance to murine filariasis.

Experimental parasitology - 1 Sept 2012

Specht Sabine, Taylor Matthew D, Hoeve Marieke A, Allen Judith E, Lang Roland, Hoerauf Achim

Abstract excerpt

Individuals infected with parasitic helminths are able to tolerate the presence of parasites for considerable time without clinical pathology. Immunosuppressive responses induced by the filarial parasite are considered responsible for this long-lasting relationship, inuring to the benefit of both parasite and host. In order to directly link IL-10 with parasite survival, we infected mice, in which over expression...

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PMID: 21959021
DOI: 10.1016/j.exppara.2011.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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