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Article

Multilocus association mapping using generalized ridge logistic regression.

BMC bioinformatics - 29 Sept 2011

Liu Zhe, Shen Yuanyuan, Ott Jurg

Abstract excerpt

BACKGROUND: In genome-wide association studies, it is widely accepted that multilocus methods are more powerful than testing single-nucleotide polymorphisms (SNPs) one at a time. Among statistical approaches considering many predictors simultaneously, scan statistics are an effective tool for detecting susceptibility genomic regions and mapping disease genes. In this study, inspired by the idea of scan...

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Identifiers

PMID: 21958005
DOI: 10.1186/1471-2105-12-384
PMCID: PMC3224109

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