Article
Hepatitis B virus X protein mutant upregulates CENP-A expression in hepatoma cells.
Oncology reports - 1 Jan 2012
Liu Lina, Li Yongmei, Zhang Shuhui, Yu Danghui, Zhu Minghua
Abstract excerpt
The carcinogenic role of hepatitis B virus x protein (HBx) in hepatocellular carcinoma (HCC) remains largely unknown. Centromere protein A (CENP-A) has been found to be frequently overexpressed in HCC. In the present study, we aimed to investigate the role of HBx in regulating CENP-A activity in HCC carcinogenesis. CENP-A expression was examined and the HBx gene was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
