Article

Mutation distribution density in tumors reconstructs human’s lost diversity

2019-09-19

Abstract excerpt

<h4>Introductory Paragraph</h4> Mutations do not accumulate uniformly across the genome. Human germline and tumor mutation density correlate poorly, and each is associated with different genomic features. Here, we analyze the genome-wide distribution of mutation densities in human and non-human Great Ape (NHGA) germlines as well as human tumors. Strikingly, non-human Great Ape germlines present higher correlation...

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Literature Corpus work: 7eeaca13-a112-5d25-ac04-078995a800c8
DOI: 10.1101/773317

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