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Article

The role of Fanconi anemia/BRCA genes in zebrafish sex determination.

Methods in cell biology - 1 Jan 2011

Rodríguez-Marí Adriana, Postlethwait John H

Abstract excerpt

Fanconi anemia (FA) is a human disease of bone marrow failure, leukemia, squamous cell carcinoma, and developmental anomalies, including hypogonadism and infertility. Bone marrow transplants improve hematopoietic phenotypes but do not prevent other cancers. FA arises from mutation in any of the 15 FANC genes that cooperate to repair double stranded DNA breaks by homologous recombination. Zebrafish has a single...

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PMID: 21951543
DOI: 10.1016/B978-0-12-381320-6.00020-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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