Article
Comparative in vitro activity of finafloxacin against staphylococci displaying normal and small colony variant phenotypes.
The Journal of antimicrobial chemotherapy - 1 Dec 2011
Idelevich Evgeny A, Kriegeskorte André, Stubbings William, Kahl Barbara C, Peters Georg, Becker Karsten
Abstract excerpt
OBJECTIVES: Staphylococcal small colony variants (SCVs) are associated with chronic and relapsing infections and their intracellular location may shield them from host defences and antibiotics. Finafloxacin is a novel fluoroquinolone that exhibits optimal activity at slightly acidic conditions where the activity of other marketed fluoroquinolones decreases. Here, the in vitro activity of finafloxacin against...
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