Article
Variant subpopulations of Staphylococcus aureus as cause of persistent and recurrent infections.
Infectious agents and disease - 1 Dec 1994
Proctor R A, Balwit J M, Vesga O
Abstract excerpt
While S. aureus small colony variants (SCVs) have been recognized in clinical materials for decades, only recently have these strains been linked to persistent, resistant, and relapsing infections. The biochemical basis for this phenotype appears to be reduced electron transport, which leads to many changes in these organisms, including decreased alpha-toxin production. Reduced alpha-toxin has been found to...
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