Article
Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.
Clinical microbiology reviews - 1 Apr 2016
Kahl Barbara C, Becker Karsten, Löffler Bettina
Abstract excerpt
Small colony variants (SCVs) were first described more than 100 years ago for Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago, an association between chronic staphylococcal infections and the presence of SCVs was observed. Since then, many clinical studies and observations have been published which tie recurrent, persistent staphylococcal infections, including device-associated...
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