Article
Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections.
Nature reviews. Microbiology - 1 Apr 2006
Proctor Richard A, von Eiff Christof, Kahl Barbara C, Becker Karsten, McNamara Peter, Herrmann Mathias, Peters Georg
Abstract excerpt
Small colony variants constitute a slow-growing subpopulation of bacteria with distinctive phenotypic and pathogenic traits. Phenotypically, small colony variants have a slow growth rate, atypical colony morphology and unusual biochemical characteristics, making them a challenge for clinical microbiologists to identify. Clinically, small colony variants are better able to persist in mammalian cells and are less...
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