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Major depressive disorder in a community-based twin sample: are there different genetic and environmental contributions for men and women?

Archives of general psychiatry - 1 Jun 1999

Bierut L J, Heath A C, Bucholz K K, Dinwiddie S H, Madden P A, Statham D J, Dunne M P, Martin N G

Abstract excerpt

BACKGROUND: Depression affects more women than men and often aggregates in families. Using a community-based sample of twins, we examined the contributions of genetic and environmental factors to the risk of developing major depressive disorder and the effect of sex and different definitions of depression on the relative contributions of genetic and environmental effects. Sex differences in genetic effects were...

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PMID: 10359473
DOI: 10.1001/archpsyc.56.6.557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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