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Article

Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease.

Neurobiology of disease - 1 Jan 2012

Botta-Orfila Teresa, Tolosa Eduard, Gelpi Ellen, Sànchez-Pla Alex, Martí Maria-José, Valldeoriola Francesc, Fernández Manel, Carmona Francesc, Ezquerra Mario

Abstract excerpt

LRRK2 mutations are the most common genetic cause of Parkinson's disease (PD). We performed a whole-genome RNA profiling of putamen tissue from idiopathic PD (IPD), LRRK2-associated PD (G2019S mutation), neurologically healthy controls and one asymptomatic LRRK2 mutation carrier, by using the Genechip Human Exon 1.0-ST Array. The differentially expressed genes found in IPD revealed an alteration of biological...

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Identifiers

PMID: 21946334
DOI: 10.1016/j.nbd.2011.08.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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