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Article

Depressive phenotypes evoked by experimental diabetes are reversed by insulin.

Physiology & behavior - 1 Feb 2012

Ho Nancy, Balu Darrick T, Hilario Monica R F, Blendy Julie A, Lucki Irwin

Abstract excerpt

Clinical studies suggest a bidirectional relationship between diabetes and depression, where diabetes may increase risk for depressive symptoms and depression may increase risk for diabetes. Preclinical models examining the effects of diabetes on brain and behavior can provide insights to the pathophysiology underlying this relationship. The current study comprehensively examined, in C57BL/6 mice, the development...

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Identifiers

PMID: 21945451
DOI: 10.1016/j.physbeh.2011.09.003
PMCID: PMC3237925

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