[Role of "oxidant-antioxidant" system and genetic biochemical polymorphism in pathogenesis of occupational allergic dermatosis].

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Article

[Role of "oxidant-antioxidant" system and genetic biochemical polymorphism in pathogenesis of occupational allergic dermatosis].

Meditsina truda i promyshlennaia ekologiia - 1 Jan 2007

Lazarashvili N A

Abstract excerpt

Studying "oxidant-antioxidant" system in patients with occupational allergic dermatosis revealed hyperactivity of free radical oxidation and depressed antioxidant system, especially its nonenzymatic unit. Finding also is high share of antibodies to double-stranded DNA in patients with occupational allergic dermatosis. Zero genotype of GSTM1 system is characterized by early (up to 5 years) development,severe...

Topics

Adult
Antibodies
Antioxidants
DNA
Dermatitis, Allergic Contact
Dermatitis, Occupational
Female
Genotype
Glutathione Transferase
Humans
Lipid Peroxidation
Male
Middle Aged
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 18035615

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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