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Article

Genetic predisposition and nongenetic risk factors of thiazolidinedione-related edema in patients with type 2 diabetes.

Pharmacogenetics and genomics - 1 Dec 2011

Chang Tien-Jyun, Liu Pi-Hua, Liang Yi-Chi, Chang Yi-Cheng, Jiang Yi-Der, Li Hung-Yuan, Lo Min-Tzu, Chen Harn-Shen, Chuang Lee-Ming

Abstract excerpt

OBJECTIVE: This study aimed to analyze the association of thiazolidinedione (TZD)-related edema with genetic and clinical variables and develop a simple points system to predict the risk of developing TZD-related edema. METHODS: Fifty-eight (21.6%) of 268 individuals who received TZD for type 2 diabetes developed peripheral edema. Twenty-eight tag single nucleotide polymorphisms (SNPs) from candidate genes...

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Source

Identifiers

PMID: 21934636
DOI: 10.1097/FPC.0b013e32834bfff1

Genes

AQP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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