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Article

Intestinal resident yeast Candida glabrata requires Cyb2p-mediated lactate assimilation to adapt in mouse intestine.

PloS one - 1 Jan 2011

Ueno Keigo, Matsumoto Yasuhiko, Uno Jun, Sasamoto Kaname, Sekimizu Kazuhisa, Kinjo Yuki, Chibana Hiroji

Abstract excerpt

The intestinal resident Candida glabrata opportunistically infects humans. However few genetic factors for adaptation in the intestine are identified in this fungus. Here we describe the C. glabrata CYB2 gene encoding lactate dehydrogenase as an adaptation factor for survival in the intestine. CYB2 was identified as a virulence factor by a silkworm infection study. To determine the function of CYB2, we analysed...

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Identifiers

PMID: 21931845
DOI: 10.1371/journal.pone.0024759
PMCID: PMC3170380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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