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Phenotype in Candida albicans of a disruption of the BGL2 gene encoding a 1,3-beta-glucosyltransferase.

Microbiology (Reading, England) - 1 Feb 1997

Sarthy Aparna V, McGonigal Thomas, Coen Michael, Frost David J, Meulbroek Jonathan A, Goldman Robert C

Abstract excerpt

The BGL2 gene encodes a unique 1,3-beta-glucosyltransferase (Bgl2p) present in the cell wall of Candida albicans and other fungi. Although believed to be involved in cell wall assembly, disruption of the gene in saccharomyces cerevisiae showed no apparent phenotype. We performed sequential disruptions of the BGL2 loci in a homozygous ura3 clinical isolate of C. albicans using the URA3 blaster method, in order to...

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PMID: 9043114
DOI: 10.1099/00221287-143-2-367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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