Article
Shh is required for Tabby hair follicle development.
Cell cycle (Georgetown, Tex.) - 1 Oct 2011
Cui Chang-Yi, Kunisada Makoto, Childress Victoria, Michel Marc, Schlessinger David
Abstract excerpt
In embryonic Eda mutant ("Tabby") mice, the development of one of the two major types of hair, "primary" hair fails, but other "secondary" hairs develop in normal numbers, though shorter and slightly aberrant. In Tabby mice, Shh is undetectable in skin early on, but is activated during secondary hair formation. We inferred that Shh may be involved in primary hair formation, activated normally by Eda, and also...
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