Article
The influence of genetic polymorphisms in XRCC3 and ADH5 genes on the frequency of genotoxicity biomarkers in workers exposed to formaldehyde.
Environmental and molecular mutagenesis - 1 Apr 2013
Ladeira Carina, Viegas Susana, Carolino Elisabete, Gomes Manuel C, Brito Miguel
Abstract excerpt
The International Agency for Research on Cancer classified formaldehyde as carcinogenic to humans because there is "sufficient epidemiological evidence that it causes nasopharyngeal cancer in humans". Genes involved in DNA repair and maintenance of genome integrity are critically involved in protecting against mutations that lead to cancer and/or inherited genetic disease. Association studies have recently...
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