Article
[Relationship between susceptibility of formaldehyde metabolism and genetic polymorphisms of ALDH2 and cytochrome P4502E1].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Aug 2008
Cheng Xue-mei, Zhao Jing, Feng Bin, Wen Pei-e, Shao Hua
Abstract excerpt
OBJECTIVE: To study the relationship between occupational hazard susceptibility of formaldehyde and genetic polymorphisms of ALDH2 and CYP2E1. METHODS: Genotypes of ALDH2 and CYP2E1 (Rsa I/Pst I site) of 107 subjects exposed to formaldehyde were determined with PCR-RFLP through testing peripheral blood lymphocytes, and the concentration of air formaldehyde in workplace and urine formic acid of the subjects were...
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