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Article

In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria.

Acta tropica - 1 Dec 2011

Folarin O A, Bustamante C, Gbotosho G O, Sowunmi A, Zalis M G, Oduola A M J, Happi C T

Abstract excerpt

Amodiaquine (AQ) is currently being used as a partner drug in combination with artesunate for treatment of uncomplicated malaria in most endemic countries of Africa. In the absence of molecular markers of artemisinin resistance, molecular markers of resistance to AQ may be useful for monitoring the development and spread of parasites resistance to Artesunate-Amodiaquine combination. This study was designed to...

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Identifiers

PMID: 21920347
DOI: 10.1016/j.actatropica.2011.08.013
PMCID: PMC3214618

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