Article
Molecular surveillance of drug-resistant Plasmodium falciparum in two distinct geographical areas of Nigeria.
Wiener klinische Wochenschrift - 1 Dec 2010
Ojurongbe Olusola, Oyedeji Segun I, Oyibo Wellington A, Fagbenro-Beyioku Adetola F, Kun Jürgen F
Abstract excerpt
Drug resistance against P. falciparum has been recognized as the crucial obstacle to curbing mortality and morbidity from malaria. We therefore determined the baseline distribution of pfcrt and pfmdr1 genes associated with resistance to chloroquine and pfdhfr gene associated with resistance to pyrimethamine in P. falciparum isolates collected from two geographically distinct areas of Nigeria. We use RT-PCR assays...
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