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Neurofilamentopathy in Neurodegenerative Diseases

26 Aug 2011

Abstract excerpt

Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and...

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PMID: 21915226
DOI: 10.2174/1874205x01105010058

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