Article
High levels of serum hepatitis B virus DNA in patients with 'anti-HBc alone': role of HBsAg mutants.
Journal of viral hepatitis - 1 Oct 2011
Launay O, Masurel J, Servant-Delmas A, Basse-Guérineau A-L, Méritet J-F, Laperche S, Sogni P, Rosenberg A R
Abstract excerpt
It remains unclear how the detection of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs) should be interpreted and whether all patients with this pattern need to be tested for hepatitis B virus (HBV)-DNA. This study aimed at reassessing the significance of 'anti-HBc alone' in unselected sera referred to the clinical laboratory and determining...
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