Article
Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia.
Blood - 10 Nov 2011
Yan Xiao-Jie, Dozmorov Igor, Li Wentian, Yancopoulos Sophia, Sison Cristina, Centola Michael, Jain Preetesh, Allen Steven L, Kolitz Jonathan E, Rai Kanti R, Chiorazzi Nicholas, Sherry Barbara
Abstract excerpt
Individual cytokines and groups of cytokines that might represent networks in chronic lymphocytic leukemia (CLL) were analyzed and their prognostic values determined. Serum levels of 23 cytokines were measured in 84 patients and 49 age-matched controls; 17 levels were significantly elevated in patients. Unsupervised hierarchical bicluster analysis identified 3 clusters (CLs) of highly correlated but...
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