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Article

FSTL5 Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma

13 Sept 2011

Abstract excerpt

PURPOSE: Integrated genomics approaches have revealed at least four distinct biologic variants of medulloblastoma: WNT (wingless), SHH (sonic hedgehog), group C, and group D. Because of the remarkable clinical heterogeneity of group D tumors and the dismal prognosis of group C patients, it is vital to identify molecular biomarkers that will allow early and effective treatment stratification in these...

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PMID: 21911727
DOI: 10.1200/jco.2011.36.2798

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