Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor.

Proceedings of the National Academy of Sciences of the United States of America - 20 Sept 2011

Lintz Mario J, Oinuma Ken-ichi, Wysoczynski Christina L, Greenberg Everett Peter, Churchill Mair E A

Abstract excerpt

Acyl-homoserine lactone (AHL) quorum sensing controls gene expression in hundreds of Proteobacteria including a number of plant and animal pathogens. Generally, the AHL receptors are members of a family of related transcription factors, and although they have been targets for development of antivirulence therapeutics there is very little structural information about this class of bacterial receptors. We have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl-Butyrolactones
Share to Circular Dichroism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crystallization

Share to Crystallography, X-Ray

Share to Protein Multimerization

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Share to Quorum Sensing

Source

Open in PubMed Open full text

Identifiers

PMID: 21911405
DOI: 10.1073/pnas.1112398108
PMCID: PMC3179110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor.PMID 21911405Read ↗

Interaction of N-3-oxododecanoyl homoserine lactone with transcriptional regulator LasR of Pseudomonas aeruginosa: Insights from molecular docking and dynamics simulationsSemantic proximity Read ↗

The conserved coordination of acyl-homoserine lactone and PqsE signaling defines the RhlR-dependent quorum-sensing network in <i>Pseudomonas aeruginosa</i> clinical isolatesSemantic proximity Read ↗

PqsE acts as an adaptor protein for the quorum-sensing transcription factor RhlR in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

An enzyme moonlights as a chaperone to control virulence of Pseudomonas aeruginosaSemantic proximity Read ↗

A novel two‐component system modulates quorum sensing and pathogenicity in Burkholderia cenocepaciaSemantic proximity Read ↗

MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.Semantic proximity Read ↗

Pleotropic potential of quorum sensing mediated N-acyl homoserine lactones (AHLs) at the LasR and RhlR receptors of Pseudomonas aeruginosaSemantic proximity Read ↗

Fine‐Tuning Covalent Inhibition of Bacterial Quorum SensingSemantic proximity Read ↗

Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

In silico identification of quorum sensing inhibitors against LasR protein in a clinical isolate of multidrug resistant Pseudomonas aeruginosa DMC-27bSemantic proximity Read ↗

Analysis of the DNA-binding domain of the <i>Pseudomonas aeruginosa</i> quorum sensing transcription factor LasRSemantic proximity Read ↗

Inhibitors of the PqsR Quorum-Sensing Receptor Reveal Differential Roles for PqsE and RhlI in Control of Phenazine ProductionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.