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Research progress on the pathogenesis of the SDHB mutation and related diseases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2023

Liu Chang, Zhou Dayang, Yang Kexin, Xu Ning, Peng Jibang, Zhu Zhu

Abstract excerpt

With the improvement of genetic testing technology in diseases in recent years, researchers have a more detailed and clear understanding of the source of cancers. Succinate dehydrogenase B (SDHB), a mitochondrial gene, is related to the metabolic activities of cells and tissues throughout the body. The mutations of SDHB have been found in pheochromocytoma, paraganglioma and other cancers, and is proved to affect...

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Identifiers

PMID: 37734265
DOI: 10.1016/j.biopha.2023.115500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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[The mutations of germline succinate dehydrogrnase subunit B (SDHB) in sporadic paragangliomas].Semantic proximity Read ↗

Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomasSemantic proximity Read ↗

15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma–paraganglioma syndromes characterized by germline SDHB and SDHD mutationsSemantic proximity Read ↗

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