Article
GATA6 reporter gene reveals myocardial phenotypic heterogeneity that is related to variations in gap junction coupling.
American journal of physiology. Heart and circulatory physiology - 1 Nov 2011
Rémond Mathieu C, Iaffaldano Grazia, O'Quinn Michael P, Mezentseva Nadejda V, Garcia Victor, Harris Brett S, Gourdie Robert G, Eisenberg Carol A, Eisenberg Leonard M
Abstract excerpt
This study examined transgenic mice whose expression of a β-galactosidase (lacZ) reporter is driven by a GATA6 gene enhancer. Previous investigations established that transcription of the transgene was associated with precardiac mesoderm and primary heart tube myocardium, which decreased progressively, so that its expression was no longer observed within ventricular myocardium by midgestation. Expression of this...
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