Article
Genetic fate-mapping for studying adult cardiomyocyte replenishment after myocardial injury.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Chan Sunny S-K, Shueh Ying-Zhang, Bustamante Nirma, Tsai Shih-Jung, Wu Hua-Lin, Chen Jyh-Hong, Hsieh Patrick C H
Abstract excerpt
Mounting evidence suggests the regenerative potential of the mammalian heart. Nevertheless, the contribution of endogenous stem or precursor cells to adult cardiac regeneration upon myocardial injuries remains unclear. We hereby describe a genetic fate-mapping approach to study adult cardiomyocyte replenishment after myocardial injury. Using double transgenic MerCreMer-ZEG mice, the fate of adult cardiomyocytes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
