Article
Development of a novel genotype-specific loop-mediated isothermal amplification technique for Hepatitis B virus genotypes B and C genotyping and quantification.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2011
Cai Zhejun, Lou Guoqiang, Cai Ting, Yang Jin, Wu Nanping
Abstract excerpt
BACKGROUND: There is the need for a rapid, economical method for genotyping Hepatitis B virus (HBV) to support clinical practice. OBJECTIVES: To develop a novel HBV genotyping process using genotype specific loop mediated isothermal amplification (LAMP). STUDY DESIGN: HBV genotypes B and C specific LAMP methods were evaluated using standard panel. A comparative analysis of the LAMP test against Taqman assay using...
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