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Article

Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats.

American journal of hypertension - 1 May 1990

Rapp J P, Wang S M, Dene H

Abstract excerpt

The cosegregation of renin alleles and blood pressure was evaluated in segregating populations derived from inbred Dahl salt hypertension sensitive (S) and inbred Dahl salt hypertension resistant (R) rats. The populations were raised on high salt diet (8% NaCl). In F2 and F1 X S populations, there was a significant positive gene-dosage relationship between the S-rat renin allele and blood pressure. In contrast,...

Topics

Alleles
Animals
Blood Pressure
Body Weight
Drug Resistance
Female
Genotype
Heart
Male
Organ Size
Rats
Rats, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Renin

Sodium Chloride

Source

Identifiers

PMID: 2190609
DOI: 10.1093/ajh/3.5.391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2190609-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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