Oncogenesis by mutations in anti-oncogenes: a view.

Article

Oncogenesis by mutations in anti-oncogenes: a view.

Anticancer research - 1 Jan 2000

Den Otter W, Koten J W, Van der Vegt B J, Beemer F A, Boxma O J, Derkinderen D J, De Graaf P W, Huber J, Lips C J, Roholl P J

Abstract excerpt

Oncogenesis is the result of accumulation of specific gene mutations. Two classes of specific cancer mutations are distinguished: namely those affecting anti-oncogenes and those in which oncogenes are involved. Anti-oncogenes are thought to regulate normal growth by encoding proteins that inhibit...

Topics

Humans
Models, Biological
Mutation
Neoplasm Staging
Neoplasms
Oncogenes
Remission, Spontaneous
Suppression, Genetic

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