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SUMO4 C438T polymorphism is associated with papulopustular skin lesion in Korean patients with Behçet's disease.

Rheumatology international - 1 Oct 2012

Park Geon, Kim Hyun-Sook, Choe Jung-Yoon, Kim Seong-Kyu

Abstract excerpt

Small ubiquitin-like modifier 4 (SUMO4) is involved in a range of autoimmune diseases and is known to downregulate the transcription activity of nuclear factor kappa B (NF-κB). Our objective was to investigate the association of a certain polymorphism (C438T) of the SUMO4 gene with Behçet's disease (BD) in terms of its incidence and clinical features in Korean patients. We consecutively enrolled 83 patients with...

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Identifiers

PMID: 21901353
DOI: 10.1007/s00296-011-2086-5

Genes

SUMO4

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